10 Noteworthy Aesthetic Clinics providing Liquid PDO Collagen Stimulator in Singapore (Ultracol 200)
- 5 days ago
- 4 min read
As aesthetic treatments continue to evolve, there is a clear shift towards regenerative skin therapies—and Ultracol 200, often referred to as a Liquid PDO Collagen Stimulator, is gaining traction in Singapore.
Unlike traditional thread lift procedures that primarily lifts the skin with the use of traditional PDO threads, Ultracol 200 works by stimulating your body’s natural collagen production using polydioxanone (PDO) microspheres. Over time, this leads to firmer skin, improved texture, and subtle structural support, delivering results that look progressively natural rather than immediate.
Often described as a “liquid threadlift”, Ultracol 200 provides a more advanced, structural approach compared to lighter skin boosters or traditional thread lifts, making it suitable for those experiencing early sagging, volume loss, and skin laxity.

What Is Traditional PDO Thread Lift?
A traditional PDO thread lift uses dissolvable threads inserted under the skin via needles or cannulas.
These threads:
Provide immediate mechanical lifting
Anchor and reposition sagging tissue
Stimulate collagen as they dissolve over time
Do note that due to the physical nature of these threads, there is a procedural risk such as thread visibility, complications from the procedure as well as dimpling.
Key Differences: Liquid vs Physical PDO Threads
Here’s a clear comparison based on mechanism, results, and patient experience:
Feature | Liquid PDO Threadlift (Ultracol) | Traditional PDO Thread Lift |
Form | Injectable liquid | Solid threads inserted under skin |
Mechanism | Collagen stimulation | Mechanical lift + collagen stimulation |
Result onset | Gradual (weeks to months) | Immediate lifting effect |
Distribution | Even, wide-area spread | Localised to thread placement |
Look | More natural, subtle | Can be more defined / structured |
Invasiveness | Minimally invasive (injections) | More invasive (entry points, threading) |
Downtime | Minimal | Mild–moderate (bruising, swelling, visible entry points) |
Risks | Lower risk of lumps/visibility | Risk of thread visibility, migration, rejection (may require removal) |
Comfort | Generally more comfortable | Can feel tight or sore initially |
Best for | Skin quality, ageing | Lifting moderate sagging |
Why Liquid PDO (Ultracol) Is Gaining Popularity
Liquid PDO threadlift or Liquid PDO Collagen Stimulators reflects a broader shift in aesthetics—from “lifting” to “regeneration.”
Key advantages include: more natural and even results, lower rejection risk, less invasive and more natural results.
When to Choose Each Treatment
Liquid PDO Threadlift (Ultracol) is ideal if you want:
Natural-looking skin tightening
Improved texture, pores, and elasticity
Preventative or early ageing treatment
Minimal downtime
Traditional PDO Threads may be better if you want:
Immediate lifting effect
More structural contouring (jawline, cheeks)
Correction of moderate sagging

Here are 10 noteworthy aesthetic clinics in Singapore offering Liquid PDO collagen stimulators like Ultracol 200.
1. MODE Medical Clinic

Mode Medical Clinic incorporates Liquid PDO Threadlift into its results-driven regenerative aesthetic portfolio, focusing on improving skin firmness, elasticity, and overall structure. Treatments are often tailored for clients seeking natural lifting effects without volumising fillers, aligning with a more refined, modern aesthetic approach.
2. V Medical Aesthetics & Laser Clinic

V Medical Aesthetics & Laser Clinic takes a technology-driven, personalised approach to skin rejuvenation. Ultracol 200 is incorporated into customised treatment plans for patients seeking gradual collagen rebuilding and long-term improvements in skin firmness, elasticity, and overall skin quality through biostimulation.
3. Glowwis Aesthetic & Medical Clinic

Glowwis Aesthetic & Medical Clinic takes a personalised, doctor-led approach to skin lifting and rejuvenation. Its Liquid PDO Thread Lift is incorporated into customised treatment plans to stimulate collagen production, improve skin firmness and elasticity, and deliver gradual, natural-looking lifting with minimal downtime.
4. ICON Medical Aesthetics

ICON Medical Aesthetics is known for its comprehensive range of non-surgical aesthetic treatments, including collagen biostimulators like Ultracol 200. The clinic typically positions the treatment as part of a preventative and restorative anti-ageing strategy, targeting early skin laxity and collagen depletion.
5. Fundamental Aesthetic Clinic

Fundamental Aesthetic Clinic adopts a medical, results-driven approach to non-surgical lifting with its Liquid PDO Thread Lift. The treatment is designed to improve skin firmness, texture, and facial contours through collagen stimulation, delivering gradual, natural-looking rejuvenation with minimal downtime.
6. MIRAE Medical Aesthetics

MIRAE Medical Aesthetics adopts a doctor-led, clinical approach to skin rejuvenation with its PDO Liquid Threadlift. The treatment is designed to stimulate collagen production, improve skin firmness and structural support, and deliver gradual, natural-looking lifting—making it suitable for individuals seeking discreet, non-surgical enhancement with minimal downtime.
7. Freia Medical

Freia Medical adopts a personalised, results-driven approach to skin rejuvenation with its PDO100 and PDO200 liquid thread treatments. These injectable biostimulators are incorporated into customised plans to stimulate collagen production, improve skin firmness and elasticity, and address concerns such as fine lines, dullness, and volume loss—delivering gradual, natural-looking rejuvenation with minimal downtime.
8. S Aesthetics Clinic Orchard
S Aesthetics provides a range of injectable treatments, including collagen stimulators designed to restore skin firmness and improve texture without drastic changes in facial volume.
Price Upon Request
9. Ei8ht Medical Aesthetics Clinic (Orchard)
Ei8ht Medical focuses on customised aesthetic solutions, where Ultracol 200 may be used as part of combination treatments for enhanced lifting and rejuvenation outcomes.
Price Upon Request
10. Om Aesthetics Clinic

Om Aesthetics emphasises non-invasive and regenerative treatments, making collagen stimulators like Ultracol 200 a suitable option for clients seeking gradual, natural skin improvement.
Price Upon Request
TWP Thoughts
Liquid PDO Threadlift—especially with innovations like Ultracol—represents a newer, more refined approach to facial rejuvenation.
Rather than lifting the face mechanically, it focuses on:
Strengthening the skin
Stimulating collagen
Delivering subtle, natural improvements over time
For patients today, the choice often comes down to this:
Do you want an instant lift—or a gradual, more natural regeneration?
Both treatments have their place, but liquid PDO is quickly becoming the preferred option for those prioritising natural results, lower risk, and minimal downtime.



